I have spent several hours trying to set up the PS to chose 1, 2, 3 or 4 extruders. Nothing I do works. I cannot believe that I have to copy the Gcode and make the various other changes each time I want to print. In researching, it sounds like this is a big weakness in Prusa Slicer but I am hoping somebody here has figured it out.
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With Bill's incredible help sorting through the maze of PS confusion, I was able to get this result: